Article
Evaluation of methods to detect CALR mutations in myeloproliferative neoplasms.
Leukemia research - 1 Jan 2015
Jones Amy V, Ward Daniel, Lyon Matthew, Leung William, Callaway Alison, Chase Andrew, Dent Carolyn L, White Helen E, Drexler Hans G, Nangalia Jyoti, Mattocks Chris, Cross Nicholas C P
Abstract excerpt
The recent discovery of somatically acquired CALR mutations in a substantial proportion of patients with myeloproliferative neoplasms has provided a new marker of clonal disease, advancing both diagnosis and prognosis in these previously difficult to characterise disorders. The mutations, which c...
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