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Nucleolus Precursor Body (NPB): A Distinct Structure in Mammalian Oocytes and Zygotes

2 Nov 2014

Abstract excerpt

Nucleoli in mammalian oocytes and zygotes, sometimes referred to as nucleolus precursor bodies (NPBs), are compact and morphologically different from nucleoli in somatic cells. We applied a unique NPB analyzing method "enucleolation" technique to zygotes to remove the NPBs. It has been reported that oocyte NPBs are essential for embryonic development; in their absence, the oocytes complete maturation and can be...

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PMID: 25495074
DOI: 10.4161/19491034.2014.990858

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