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Nuclear reprogramming of sperm and somatic nuclei in eggs and oocytes

3 Jun 2013

Abstract excerpt

Eggs and oocytes have a prominent ability to reprogram sperm nuclei for ensuring embryonic development. The reprogramming activity that eggs/oocytes intrinsically have towards sperm is utilised to reprogram somatic nuclei injected into eggs/oocytes in nuclear transfer (NT) embryos. NT embryos of various species can give rise to cloned animals, demonstrating that eggs/oocytes can confer totipotency even to somatic...

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PMID: 24273450
DOI: 10.1007/s12522-013-0155-z

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