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Article

Noncoding <scp>RNA</scp> blockade of autophagy is therapeutic in medullary thyroid cancer

8 Dec 2014

Abstract excerpt

Micro-RNAs are dysregulated in medullary thyroid carcinoma (MTC) and preliminary studies have shown that miRNAs may enact a therapeutic effect through changes in autophagic flux. Our aim was to study the in vitro effect of miR-9-3p on MTC cell viability, autophagy and to investigate the mRNA autophagy gene profile of sporadic versus hereditary MTC. The therapeutic role of miR-9-3p was investigated in vitro using...

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PMID: 25487826
DOI: 10.1002/cam4.355

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