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Article

Overexpression of miR-10a and miR-375 and downregulation of YAP1 in medullary thyroid carcinoma.

Experimental and molecular pathology - 1 Aug 2013

Hudson Jena, Duncavage Eric, Tamburrino Anna, Salerno Paolo, Xi Liqiang, Raffeld Mark, Moley Jeffrey, Chernock Rebecca D

Abstract excerpt

MicroRNAs are a primordial mechanism of gene expression control that appear to be crucial to cellular development and may play an important role in tumor development. Much is known about the genetics of medullary thyroid carcinomas, as approximately 25% are hereditary and harbor germ line activating mutations in the RET gene. Somatic RET mutations are also seen in roughly 50% of sporadic medullary thyroid...

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Identifiers

PMID: 23685355
DOI: 10.1016/j.yexmp.2013.05.001
PMCID: PMC3712278

Genes

RET
YAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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