Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Knockdown of Atg7 Induces Nuclear-LC3 Dependent Apoptosis and Augments Chemotherapy in Colorectal Cancer Cells

7 Feb 2020

Abstract excerpt

Autophagy is a catabolic process that enables cells to degrade obsolete content and refuel energy depots. In colorectal cancer (CRC) autophagy has been shown to promote tumorigenesis through energy delivery in the condition of uncontrolled proliferation. With this study, we aimed at evaluating whether autophagy sustains CRC cell viability and if it impacts therapy resistance. Initially, a colorectal cancer tissue...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Endoplasmic Reticulum Stress and Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32046105
DOI: 10.3390/ijms21031099

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Knockdown of Atg7 Induces Nuclear-LC3 Dependent Apoptosis and Augments Chemotherapy in Colorectal Cancer CellsPMID 32046105Read ↗

Autophagy in colorectal cancer: An important switch from physiology to pathologySemantic proximity Read ↗

Autophagy in colorectal cancer: Current understanding of mechanisms and future therapeutic directionsSemantic proximity Read ↗

Curcumin and its anti‐colorectal cancer potential: From mechanisms of action to autophagySemantic proximity Read ↗

Autophagy Is Activated in Colorectal Cancer Cells and Contributes to the Tolerance to Nutrient DeprivationSemantic proximity Read ↗

Natural Compounds Targeting the Autophagy Pathway in the Treatment of Colorectal CancerSemantic proximity Read ↗

Autophagy-related lncRNAs and exosomal lncRNAs in colorectal cancer: focusing on lncRNA-targeted strategiesSemantic proximity Read ↗

Molecular and cellular pathways in colorectal cancer: apoptosis, autophagy and inflammation as key playersSemantic proximity Read ↗

The effect of miRNA and autophagy on colorectal cancerSemantic proximity Read ↗

miR-106a suppresses tumor cells death in colorectal cancer through targeting ATG7Semantic proximity Read ↗

Colorectal cancer cells respond differentially to autophagy inhibition in vivoSemantic proximity Read ↗

Different Roles of Apoptosis and Autophagy in the Development of Human Colorectal CancerSemantic proximity Read ↗

Functions and Implications of Autophagy in Colon CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.