Genetic variants of glutamate receptor gene family in Taiwanese Kawasaki disease children with coronary artery aneurysms

Abstract excerpt

BACKGROUND: Patients with Kawasaki disease (KD), a pediatric systemic vasculitis, may develop coronary artery aneurysm (CAA) as a complication. To investigate the role of glutamate receptors in KD and its CAA development, we performed genetic association studies. METHODS AND RESULTS: We examined the whole family of glutamate receptors by genetic association studies in a Taiwanese cohort of 262 KD patients. We...

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