Integrin α2 gene polymorphism is a risk factor of coronary artery lesions in Chinese children with Kawasaki disease.

doi:10.1186/s12969-021-00494-5

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Article

Integrin α2 gene polymorphism is a risk factor of coronary artery lesions in Chinese children with Kawasaki disease.

Pediatric rheumatology online journal - 8 Feb 2021

Yuan Jia, Jiang Zhiyong, Li Meiai, Li Wei, Gu Xueping, Wang Zhouping, Pi Lei, Xu Yufen, Zhou Huazhong, Zhang Baidu, Deng Qiulian, Wang Yanfei, Huang Ping, Zhang Li, Gu Xiaoqiong

Abstract excerpt

BACKGROUND: Kawasaki disease (KD) is a systemic vasculitis, and the formation of coronary artery lesions(CAL) is its most common sequela. Both genetic and environmental factors are considered to be important factors of in KD. Integrin α2 (ITGA2) is a transmembrane receptor that is associated with susceptibility to several diseases, but its relevance to KD with CAL is unclear. METHODS: We genotyped ITGA2 rs1126643...

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PMID: 33557870
DOI: 10.1186/s12969-021-00494-5
PMCID: PMC7869497

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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