Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of autophagy by E3 ubiquitin ligase RNF216 through BECN1 ubiquitination

11 Nov 2014

Abstract excerpt

Autophagy is an evolutionarily conserved biological process involved in an array of physiological and pathological events. Without proper control, autophagy contributes to various disorders, including cancer and autoimmune and inflammatory diseases. It is therefore of vital importance that autophagy is under careful balance. Thus, additional regulators undoubtedly deepen our understanding of the working network,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 25484083
DOI: 10.4161/15548627.2014.981792

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of autophagy by E3 ubiquitin ligase RNF216 through BECN1 ubiquitinationPMID 25484083Read ↗

Ubiquitination of ATF6 by disease-associated RNF186 promotes the innate receptor-induced unfolded protein response.Semantic proximity Read ↗

Autophagy Regulation by Crosstalk between miRNAs and Ubiquitination SystemSemantic proximity Read ↗

Bacterial ubiquitin ligases hijack the host deubiquitinase OTUB1 to inhibit MTORC1 signaling and promote autophagySemantic proximity Read ↗

The exploitation of host autophagy and ubiquitin machinery by <i>Mycobacterium tuberculosis</i> in shaping immune responses and host defense during infectionSemantic proximity Read ↗

USP8 regulates liver cancer progression via the inhibition of TRAF6-mediated signal for NF-κB activation and autophagy induction by TLR4Semantic proximity Read ↗

Induced TRIM21 ISGylation by IFN-β enhances p62 ubiquitination to prevent its autophagosome targetingSemantic proximity Read ↗

RING1 dictates GSDMD-mediated inflammatory response and host susceptibility to pathogen infectionSemantic proximity Read ↗

The Ubiquitin Ligase Smurf1 Functions in Selective Autophagy of Mycobacterium tuberculosis and Anti-tuberculous Host DefenseSemantic proximity Read ↗

The Ubiquitin Ligase Smurf1 Functions in Selective Autophagy of Mycobacterium tuberculosis and Anti-tuberculous Host DefenseSemantic proximity Read ↗

RNF2 is recruited by WASH to ubiquitinate AMBRA1 leading to downregulation of autophagySemantic proximity Read ↗

RNF216 Variants Found in Patients With Dementia, Hypogonadotropic Hypogonadism, and Severe Ataxia Deregulate Autophagy.Semantic proximity Read ↗

Macrophage TRIM21 knockout inhibits septic acute lung injury by downregulating autophagy regulator protein ubiquitinationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.