Article
Evaluation of IFN-γ polymorphism+874 T/A in patients with recurrent tonsillitis by PCR real time mismatch amplification mutation assay (MAMA real time PCR).
Cytokine - 1 Feb 2015
Bergallo Massimiliano, Gambarino Stefano, Loiacono Elisa, Vergano Luca, Galliano Ilaria, Montanari Paola, Astegiano Sara, Tavormina Paolo, Tovo Pier-Angelo
Abstract excerpt
Interferon gamma (IFN-γ) is an important cytokine that plays a crucial role in the balance between normal and pathological immune response. Defect of IFN-γ can give a predisposition to infectious disease, autoimmune pathologies and tumours. Different polymorphisms in this gene have been described, in particular the single nucleotide polymorphism (SNP)+874∗T/A that may affect IFN-γ gene expression. Several...
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