Article
Interleukin-2, Interferon-gamma Gene Polymorphisms in Recurrent Aphthous Stomatitis.
Prague medical report - 1 Jan 2000
Najafi Shamsolmoulouk, Yousefi Hila, Mohammadzadeh Mahsa, Bidoki Alireza Zare, Farhadi Elham, Rezaei Nima
Abstract excerpt
Recurrent aphthous stomatitis (RAS) is the most common oral ulcerative inflammatory disease with unknown etiology. IL-2 and IFN-γ are secreted by Th1 cells and the elevated levels of them have been reported in RAS. Single nucleotide polymorphisms (SNPs) of IL-2 and IFN-γ genes could alter the cytokine production. The aim of this study was to investigate frequencies of IL-2 and IFN-γ alleles and genotypes in a...
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