Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Toll-dorsal pathway is required for resistance to viral oral infection in Drosophila.

PLoS pathogens - 1 Dec 2014

Ferreira Álvaro Gil, Naylor Huw, Esteves Sara Santana, Pais Inês Silva, Martins Nelson Eduardo, Teixeira Luis

Abstract excerpt

Pathogen entry route can have a strong impact on the result of microbial infections in different hosts, including insects. Drosophila melanogaster has been a successful model system to study the immune response to systemic viral infection. Here we investigate the role of the Toll pathway in resistance to oral viral infection in D. melanogaster. We show that several Toll pathway components, including Spätzle,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drosophila melanogaster
Share to Drosophila Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunity, Innate

Share to Nuclear Proteins

Share to Phosphoproteins

Share to Picornaviridae

Share to Toll-Like Receptors

Share to Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 25473839
DOI: 10.1371/journal.ppat.1004507
PMCID: PMC4256459

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Toll-dorsal pathway is required for resistance to viral oral infection in Drosophila.PMID 25473839Read ↗

The Aedes aegypti Toll Pathway Controls Dengue Virus InfectionSemantic proximity Read ↗

The Toll pathway is important for an antiviral response in <i>Drosophila</i>Semantic proximity Read ↗

Innate antiviral immunity in DrosophilaSemantic proximity Read ↗

RNA interference directs innate immunity against viruses in adult Drosophila.Semantic proximity Read ↗

Drosophila melanogaster Mounts a Unique Immune Response to the Rhabdovirus Sigma virusSemantic proximity Read ↗

RNAi screening identifies a new Toll from shrimp that restricts WSSV infection through activating Dorsal to induce antimicrobial peptidesSemantic proximity Read ↗

RNAi screening identifies a new Toll from shrimp Litopenaeus vannamei that restricts WSSV infection through activating Dorsal to induce antimicrobial peptidesSemantic proximity Read ↗

Induced antiviral innate immunity in DrosophilaSemantic proximity Read ↗

Viruses in Laboratory Drosophila and Their Impact on Host Gene ExpressionSemantic proximity Read ↗

Antiviral immunity in drosophilaSemantic proximity Read ↗

The Drosophila Toll Pathway in Innate Immunity: from the Core Pathway toward Effector FunctionsSemantic proximity Read ↗

Genetic determinants of antiviral immunity in dipteran insects – Compiling the experimental evidenceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.