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Article

The Aedes aegypti Toll Pathway Controls Dengue Virus Infection

3 Jul 2008

Abstract excerpt

Aedes aegypti, the mosquito vector of dengue viruses, utilizes its innate immune system to ward off a variety of pathogens, some of which can cause disease in humans. To date, the features of insects' innate immune defenses against viruses have mainly been studied in the fruit fly Drosophila melanogaster, which appears to utilize different immune pathways against different types of viruses, in addition to an RNA...

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PMID: 18604274
DOI: 10.1371/journal.ppat.1000098

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