Article

RNAi screening identifies a new Toll from shrimp that restricts WSSV infection through activating Dorsal to induce antimicrobial peptides

2018-07-09

Abstract excerpt

<h4>ABSTRACT</h4> The function of Toll pathway defense against bacterial infection has been well established in shrimp, however how this pathway responds to viral infection is still largely unknown. In this study, we report the Toll4-Dorsal-AMPs cascade restricts the white spot syndrome virus (WSSV) infection of shrimp. A total of nine Tolls from Litopenaeus vannamei namely Toll1-9 are identified, and RNAi scree...

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Literature Corpus work: b89e2be2-2704-5669-9151-2f03714f0874
DOI: 10.1101/365197

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