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Article

Surfactant protein D attenuates sub-epithelial fibrosis in allergic airways disease through TGF-β.

Respiratory research - 29 Nov 2014

Ogawa Hirohisa, Ledford Julie G, Mukherjee Sambuddho, Aono Yoshinori, Nishioka Yasuhiko, Lee James J, Izumi Keisuke, Hollingsworth John W

Abstract excerpt

BACKGROUND: Surfactant protein D (SP-D) can regulate both innate and adaptive immunity. Recently, SP-D has been shown to contribute to the pathogenesis of airway allergic inflammation and bleomycin-induced pulmonary fibrosis. However, in allergic airways disease, the role of SP-D in airway remodeling remains unknown. The objective of this study was to determine the contribution of functional SP-D in regulating...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25472740
DOI: 10.1186/s12931-014-0143-9
PMCID: PMC4262976

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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