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Article

The miR526b-5p-Related Single Nucleotide Polymorphisms, rs72618599, Located in 3'-UTR of TCF3 Gene, is Associated with the Risk of Breast and Gastric Cancers

Iranian biomedical journal - 1 Jan 2022

Mohammadi Maryam, Salehzadeh Ali, Talesh Sasani Soheila, Tarang Alireza

Abstract excerpt

Background: Single nucleotide polymorphisms result in dysregulation of the proto-oncogene TCF3 gene, which is associated with the development, metastasis, and chemoresistance of different malignancies. Methods: GSE10810 microarray dataset and GEPIA2 online software were used to find differentially expressed genes and the TCF3 status in breast cancer (BC) and gastric cancer (GC), respectively. Plots and figures of...

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PMID: 34700372
DOI: 10.52547/ibj.26.1.53
PMCID: PMC8784898

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