Article
Genetic polymorphism at miR-181a binding site contributes to gastric cancer susceptibility.
Carcinogenesis - 1 Dec 2012
Lin Yong, Nie Yuqiang, Zhao Jing, Chen Xi, Ye Min, Li Yingfei, Du Yanlei, Cao Jie, Shen Bo, Li Yuyuan
Abstract excerpt
Recent evidences show that genetic polymorphisms falling in miRNA binding sites can alter the strength of miRNA binding and disturb miRNA-mediated posttranscriptional regulation. Our study aimed to investigate the role of single-nucleotide polymorphisms (SNPs) in putative miRNA binding sites in g...
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