Article
Association of genetic polymorphisms for glutathione peroxidase genes with obesity in Spanish children.
Journal of nutrigenetics and nutrigenomics - 1 Jan 2014
Rupérez Azahara I, Olza Josune, Gil-Campos Mercedes, Leis Rosaura, Mesa María Dolores, Tojo Rafael, Cañete Ramón, Gil Ángel, Aguilera Concepción M
Abstract excerpt
BACKGROUND/AIMS: Altered expression and activity of the antioxidant enzymes glutathione peroxidases (GPXs) have been observed in obesity in human and animal studies. We aimed to study 59 single nucleotide polymorphisms (SNPs) for GPX1-7 genes and to characterize their association with prepubertal childhood obesity and its associated biomarkers. METHODS: This case-control study included 193 obese and 191...
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