Article
Reappraising the relationship between mitochondrial DNA variant m.16189T>C and type 2 diabetes mellitus in East Asian populations.
Current molecular medicine - 1 Jan 2014
Zhong L, Tang J, Kong Q-P, Sun C, Zhou W-P, Yang M, Yao Y-G, Zhang Y-P
Abstract excerpt
The role of mitochondrial DNA (mtDNA) variant 16189T>C in type 2 diabetes mellitus (T2DM) remains hotly debated in the past decade. If mutation 16189T>C indeed posed a risk to T2DM, as echoed by some recent studies, correlation between this mutation and disease should be observed when carrying out a systematical study using data and samples collected in a large geographic region in China. To test this hypothesis,...
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