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Article

Erythrocytic α-Synuclein as a potential biomarker for Parkinson’s disease

15 May 2019

Abstract excerpt

BACKGROUND: Erythrocytes are a major source of peripheral α-synuclein (α-Syn). The goal of the current investigation is to evaluate erythrocytic total, oligomeric/aggregated, and phosphorylated α-Syn species as biomarkers of Parkinson's disease (PD). PD and healthy control blood samples were collected along with extensive clinical history to determine whether total, phosphorylated, or aggregated α-Syn derived...

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PMID: 31123587
DOI: 10.1186/s40035-019-0155-y

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