Article
Batf3 deficiency is not critical for the generation of CD8α⁺ dendritic cells.
Immunobiology - 1 Apr 2015
Mott Kevin R, Maazi Hadi, Allen Sariah J, Zandian Mandana, Matundan Harry, Ghiasi Yasamin N, Sharifi Behrooz G, Underhill David, Akbari Omid, Ghiasi Homayon
Abstract excerpt
Recently, we have reported that CD8α(+) DCs, rather than CD8(+) T cells, are involved in the establishment and maintenance of HSV-1 latency in the trigeminal ganglia (TG) of ocularly infected mice. In the current study, we investigated whether similar results can be obtained using Batf3(-/-) mice that previously were reported to lack CD8α(+) DCs. However, our results demonstrate that Batf3(-/-) mice, without any...
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