Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lymphoid-Related CD11c + CD8α + Dendritic Cells Are Involved in Enhancing Herpes Simplex Virus Type 1 Latency

30 Jul 2008

Abstract excerpt

The mechanism(s) by which herpes simplex virus type 1 (HSV-1) latency is established in neurons is not known. In this study, we examined the effect of dendritic cells (DCs) on the level of HSV-1 latency in trigeminal ganglia (TGs) of ocularly infected BALB/c and C57BL/6 mice. We found that immunization of wild-type mice with FMS-like tyrosine kinase 3 ligand (Flt3L) DNA, which increases the number of DCs,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Herpesvirus Infections and Treatments
Share to Immunotherapy and Immune Responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18667491
DOI: 10.1128/jvi.00566-08

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lymphoid-Related CD11c + CD8α + Dendritic Cells Are Involved in Enhancing Herpes Simplex Virus Type 1 LatencyPMID 18667491Read ↗

The herpes simplex virus type 1 latency-associated transcript inhibits phenotypic and functional maturation of dendritic cells.Semantic proximity Read ↗

Broadening the Repertoire of Functional Herpes Simplex Virus Type 1–Specific CD8+ T Cells Reduces Viral Reactivation from Latency in Sensory GangliaSemantic proximity Read ↗

Interferon Regulator Factor 8 (IRF8) Limits Ocular Pathology during HSV-1 Infection by Restraining the Activation and Expansion of CD8+ T Cells.Semantic proximity Read ↗

Batf3 deficiency is not critical for the generation of CD8α⁺ dendritic cells.Semantic proximity Read ↗

Cd8+ T Cells Can Block Herpes Simplex Virus Type 1 (HSV-1) Reactivation from Latency in Sensory NeuronsSemantic proximity Read ↗

Thymidine Kinase-Negative Herpes Simplex Virus 1 Can Efficiently Establish Persistent Infection in Neural Tissues of Nude Mice.Semantic proximity Read ↗

Expression of Herpes Simplex Virus 1-Encoded MicroRNAs in Human Trigeminal Ganglia and Their Relation to Local T-Cell InfiltratesSemantic proximity Read ↗

Disease-modifying capability of murine Flt3-ligand DCs in experimental autoimmune encephalomyelitis.Semantic proximity Read ↗

An Engineered Herpesvirus Activates Dendritic Cells and Induces Protective Immunity.Semantic proximity Read ↗

Herpes simplex virus 1 microRNAs expressed abundantly during latent infection are not essential for latency in mouse trigeminal gangliaSemantic proximity Read ↗

CD8+ T cells control corneal disease following ocular infection with herpes simplex virus type 1Semantic proximity Read ↗

Bioluminescence Imaging Reveals Systemic Dissemination of Herpes Simplex Virus Type 1 in the Absence of Interferon ReceptorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.