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Article

Genetic Variants Associated With the Onset and Progression of Primary Open-Angle Glaucoma.

American journal of ophthalmology - 1 Jul 2020

Mabuchi Fumihiko, Mabuchi Nakako, Sakurada Yoichi, Yoneyama Seigo, Kashiwagi Kenji, Iijima Hiroyuki, Yamagata Zentaro, Takamoto Mitsuko, Aihara Makoto, Iwata Takeshi, Hashimoto Kazuki, Sato Kota, Shiga Yukihiro, Nishiguchi Koji M, Nakazawa Toru, Akiyama Masato, Kawase Kazuhide, Ozaki Mineo, Araie Makoto

Abstract excerpt

PURPOSE: We sought to investigate the genetic variants associated with the onset and progression of primary open-angle glaucoma (POAG). DESIGN: Case-control genetic association study. METHODS: Japanese POAG patients (n = 505) and control subjects (n = 246) were genotyped for 22 genetic variants predisposing to POAG that can be classified into those associated with intraocular pressure (IOP) elevation (IOP-related...

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Identifiers

PMID: 32217119
DOI: 10.1016/j.ajo.2020.03.014

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