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Article

Expression of marA is remarkably increased from the early stage of development of fluoroquinolone-resistance in uropathogenic Escherichia coli.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Feb 2015

Yamasaki Eiki, Yamada Chihiro, Jin Xinghua, Nair G Balakrish, Kurazono Hisao, Yamamoto Shingo

Abstract excerpt

BACKGROUND: Analyses of efflux pumps overexpression and mutations in quinolone resistance determining region (QRDR) in early stage of development of resistance to fluoroquinolones (FQs) are valuable to discuss countermeasures against them. We induced levofloxacin (LVFX)-resistant strains from susceptible uropathogenic Escherichia coli in vitro to analyze the mechanisms of development of FQs-resistance. METHODS:...

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Identifiers

PMID: 25456896
DOI: 10.1016/j.jiac.2014.10.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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