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Article

Antibiotic Combination to Effectively Postpone or Inhibit the In Vitro Induction and Selection of Levofloxacin-Resistant Mutants in Elizabethkingia anophelis.

International journal of molecular sciences - 12 Feb 2024

Lee Ching-Chi, Lai Chung-Hsu, Yang Chih-Hui, Huang Yi-Han, Lin Jiun-Nong

Abstract excerpt

Fluoroquinolones are potentially active against Elizabethkingia anophelis. Rapidly increased minimum inhibitory concentrations (MICs) and emerging point mutations in the quinolone resistance-determining regions (QRDRs) following exposure to fluoroquinolones have been reported in E. anophelis. We aimed to investigate point mutations in QRDRs through exposure to levofloxacin (1 × MIC) combinations with different...

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Identifiers

PMID: 38396892
DOI: 10.3390/ijms25042215
PMCID: PMC10889675

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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