Multiple antibiotic resistance (mar) locus protects Escherichia coli from rapid cell killing by fluoroquinolones.

doi:10.1128/AAC.40.5.1266

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Article

Multiple antibiotic resistance (mar) locus protects Escherichia coli from rapid cell killing by fluoroquinolones.

Antimicrobial agents and chemotherapy - 1 May 1996

Goldman J D, White D G, Levy S B

Abstract excerpt

The multiple antibiotic resistance (mar) locus in Escherichia coli consists of two divergently expressed operons (marC and marRAB), both of which contribute to the Mar phenotype. Overexpression of the marRAB operon protected E. coli against rapid cell killing by fluoroquinolones. Inactivation of...

Topics

Anti-Infective Agents
Chromosomes, Bacterial
Drug Resistance, Microbial
Drug Resistance, Multiple
Escherichia coli
Kanamycin Resistance
Microbial Sensitivity Tests
Mutation
Norfloxacin
Operon
Phenotype
Plasmids

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