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Article

Emergence of fluoroquinolone resistance and possible mechanisms in clinical isolates of Stenotrophomonas maltophilia from Iran.

Scientific reports - 5 May 2021

Azimi Akram, Rezaei Farhad, Yaseri Mehdi, Jafari Sirus, Rahbar Mohammad, Douraghi Masoumeh

Abstract excerpt

Stenotrophomonas maltophilia exhibits wide spectrum of fluoroquinolone resistance using different mechanisms as multidrug efflux pumps and Smqnr alleles. Here, the role of smeDEF, smeVWX efflux genes and contribution of Smqnr alleles in the development of fluoroquinolone resistance was assessed. Ciprofloxacin, levofloxacin and moxifloxacin resistance were found in 10.9%, 3.5%, and 1.6% of isolates, respectively....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33953262
DOI: 10.1038/s41598-021-88977-z
PMCID: PMC8100118

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