Article
Genetic and functional analysis of the TBX3 gene promoter in indirect inguinal hernia.
Gene - 1 Jan 2015
Zhao Zhongqing, Tian Wenjun, Wang Lin, Wang Haihua, Qin Xianyun, Xing Qining, Pang Shuchao, Yan Bo
Abstract excerpt
Inguinal hernia is a common developmental disease in children and most cases are indirect inguinal hernia (IIH). Genetic factors have been suggested to play important roles in IIH. Although IIH has been observed in several human syndromes, genetic causes and molecular mechanisms for IIH remain unknown. TBX3 is a member of the T-box family of transcription factors that are essential to the embryonic development....
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