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Article

COPD-related adenocarcinoma presents low aggressiveness morphological and molecular features compared to smoker tumours.

Lung cancer (Amsterdam, Netherlands) - 1 Dec 2014

Schiavon Marco, Marulli Giuseppe, Nannini Nazarena, Pasello Giulia, Lunardi Francesca, Balestro Elisabetta, Perissinotto Egle, Rebusso Alessandro, Saetta Marina, Rea Federico, Calabrese Fiorella

Abstract excerpt

OBJECTIVES: Adenocarcinoma comprises a group of diseases with heterogeneous clinical and molecular characteristics. COPD and lung cancer are strictly related; to date it is unknown if COPD-associated cancers have different features from tumours arising in non-COPD patients. Our aim was to study COPD-associated adenocarcinoma phenotypes mainly focusing on morphological and molecular aspects, in comparison to...

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PMID: 25454198
DOI: 10.1016/j.lungcan.2014.10.004

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KRAS
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