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Decreased A20 mRNA and protein expression in peripheral blood mononuclear cells in patients with type 2 diabetes and latent autoimmune diabetes in adults.

Diabetes research and clinical practice - 1 Dec 2014

Cheng Liqing, Zhang Dongmei, Jiang Youzhao, Deng Wuquan, Wu Qi'nan, Jiang Xiaoyan, Chen Bing

Abstract excerpt

AIMS: A20 is a negative regulator of nuclear factor kappa B activation and the central gatekeeper in inflammation and immunity. While its role in type 1 diabetes has been widely studied, its expression level in immune cells from type 2 diabetes (T2D) and latent autoimmune diabetes in adult (LADA) patients remains unclear. This study aimed to clarify whether the expression of A20 is altered in patients with T2D or...

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Identifiers

PMID: 25451900
DOI: 10.1016/j.diabres.2014.09.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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