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Article

Collagen type V promotes the malignant phenotype of pancreatic ductal adenocarcinoma.

Cancer letters - 28 Jan 2015

Berchtold Sonja, Grünwald Barbara, Krüger Achim, Reithmeier Anja, Hähl Teresa, Cheng Tao, Feuchtinger Annette, Born Diana, Erkan Mert, Kleeff Jörg, Esposito Irene

Abstract excerpt

Excessive matrix production by pancreatic stellate cells promotes local growth and metastasis of pancreatic ductal adenocarcinoma and provides a barrier for drug delivery. Collagen type V is a fibrillar, regulatory collagen up-regulated in the stroma of different malignant tumors. Here we show that collagen type V is expressed by pancreatic stellate cells in the stroma of pancreatic ductal adenocarcinoma and...

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Source

Identifiers

PMID: 25449434
DOI: 10.1016/j.canlet.2014.10.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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