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Article

PTPN22 R620W polymorphism and ANCA disease risk in white populations: a metaanalysis.

The Journal of rheumatology - 1 Feb 2015

Cao Yali, Liu Kuo, Tian Zhigang, Hogan Susan L, Yang Jiajin, Poulton Caroline J, Falk Ronald J, Li Wenge

Abstract excerpt

OBJECTIVE: No clear consensus has been reached on the PTPN22 R620W polymorphism and anti-neutrophil cytoplasmic antibody (ANCA) disease, especially when stratified by ANCA specificity and disease phenotypes. METHODS: A metaanalysis was conducted on the PTPN22 R620W polymorphism across 4 studies in 1399 white patients with ANCA disease and 9934 normal control subjects. RESULTS: Overall, metaanalysis showed a...

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Share to Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antibodies, Antineutrophil Cytoplasmic

Share to PTPN22 gene

Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

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Source

Open in PubMed Open full text

Identifiers

PMID: 25448792
DOI: 10.3899/jrheum.131430
PMCID: PMC4314360

Genes

PTPN22

Variants

Provenance

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