Article
The allele frequency of T920C mutation in butyrylcholinesterase gene is high in an Indian population.
Gene - 25 Jan 2015
David Swapna Merlin, Soundararajan Lalitha, Boopathy Rathanam
Abstract excerpt
The genetic variants of butyrylcholinesterase (BChE) are the cause of concern in individuals experiencing prolonged apnea on administration of muscle relaxants. In an Indian community called Vysya, a variant (L307P; T920C) was associated with imperceptible plasma BChE. Since BChE has several pharmacological significances in humans, the identification of its variants having altered activity is very important....
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