Article
Frequency and enzyme activity of the butyrylcholinesterase K-variant in a Turkish population.
European journal of clinical pharmacology - 1 Feb 2004
Babaoglu Melih O, Ocal Turgay, Bayar Banu, Kayaalp S Oguz, Bozkurt Atila
Abstract excerpt
OBJECTIVE: Among variants of the butyrylcholinesterase gene ( BChE), the K-variant causing Ala539Thr substitution is the most common one associated with about one-third reduction in the enzyme activity. This study aimed to detect the frequency of the K-variant allele in a Turkish population sample and also to evaluate how the plasma BChE activity was influenced by this variant. METHODS: Patients administered for...
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