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Article

Frequency and enzyme activity of the butyrylcholinesterase K-variant in a Turkish population.

European journal of clinical pharmacology - 1 Feb 2004

Babaoglu Melih O, Ocal Turgay, Bayar Banu, Kayaalp S Oguz, Bozkurt Atila

Abstract excerpt

OBJECTIVE: Among variants of the butyrylcholinesterase gene ( BChE), the K-variant causing Ala539Thr substitution is the most common one associated with about one-third reduction in the enzyme activity. This study aimed to detect the frequency of the K-variant allele in a Turkish population sample and also to evaluate how the plasma BChE activity was influenced by this variant. METHODS: Patients administered for...

Topics

Adult
Alleles
Butyrylcholinesterase
Female
Genetics, Population
Genotype
Humans
Male
Pharmacogenetics
Turkey

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 14735258
DOI: 10.1007/s00228-003-0716-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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