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Article

Analysis of the AHR gene proximal promoter GGGGC-repeat polymorphism in lung, breast, and colon cancer.

Toxicology and applied pharmacology - 1 Jan 2015

Spink Barbara C, Bloom Michael S, Wu Susan, Sell Stewart, Schneider Erasmus, Ding Xinxin, Spink David C

Abstract excerpt

The aryl hydrocarbon receptor (AhR) regulates expression of numerous genes, including those of the CYP1 gene family. With the goal of determining factors that control AHR gene expression, our studies are focused on the role of the short tandem repeat polymorphism, (GGGGC)n, located in the proximal promoter of the human AHR gene. When luciferase constructs containing varying GGGGC repeats were transfected into...

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Source

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Identifiers

PMID: 25447411
DOI: 10.1016/j.taap.2014.10.017
PMCID: PMC4404625

Genes

AHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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