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Article

Biomechanical properties of bone in a mouse model of Rett syndrome.

Bone - 1 Feb 2015

Kamal Bushra, Russell David, Payne Anthony, Constante Diogo, Tanner K Elizabeth, Isaksson Hanna, Mathavan Neashan, Cobb Stuart R

Abstract excerpt

Rett syndrome (RTT) is an X-linked genetic disorder and a major cause of intellectual disability in girls. Mutations in the methyl-CpG binding protein 2 (MECP2) gene are the primary cause of the disorder. Despite the dominant neurological phenotypes, MECP2 is expressed ubiquitously throughout the body and a number of peripheral phenotypes such as scoliosis, reduced bone mineral density and skeletal fractures are...

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Source

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Identifiers

PMID: 25445449
DOI: 10.1016/j.bone.2014.10.008
PMCID: PMC4289916

Genes

MECP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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