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Article

Skeletal abnormalities in mice with Dnmt3a missense mutations.

Bone - 1 Jun 2024

Bell-Hensley Austin, Beard Diana C, Feeney Kathryn, Zheng Hongjun, Jiang Yunhao, Zhang Xiyun, Liu Jin, Gabel Harrison, McAlinden Audrey

Abstract excerpt

Overgrowth and intellectual disability disorders in humans are typified by length/height and/or head circumference ≥ 2 standard deviations above the mean as well as intellectual disability and behavioral comorbidities, including autism and anxiety. Tatton-Brown-Rahman Syndrome is one type of overgrowth and intellectual disability disorder caused by heterozygous missense mutations in the DNA methyltransferase 3A...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38522809
DOI: 10.1016/j.bone.2024.117085
PMCID: PMC11057337

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