Article
Genomic and genetic variation in E2F transcription factor-1 in men with nonobstructive azoospermia.
Fertility and sterility - 1 Jan 2015
Jorgez Carolina J, Wilken Nathan, Addai Josephine B, Newberg Justin, Vangapandu Hima V, Pastuszak Alexander W, Mukherjee Sarmistha, Rosenfeld Jill A, Lipshultz Larry I, Lamb Dolores J
Abstract excerpt
OBJECTIVE: To identify gene dosage changes associated with nonobstructive azoospermia (NOA) using array comparative genomic hybridization (aCGH). DESIGN: Prospective study. SETTING: Medical school. PATIENT(S): One hundred ten men with NOA and 78 fertile controls. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): The study has four distinct analytic components: aCGH, a molecular karyotype that detects copy number...
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