Article
Integrative DNA methylation and gene expression analysis identifies discoidin domain receptor 1 association with idiopathic nonobstructive azoospermia.
Fertility and sterility - 1 Oct 2014
Ramasamy Ranjith, Ridgeway Alex, Lipshultz Larry I, Lamb Dolores J
Abstract excerpt
OBJECTIVE: To evaluate the association between promoter DNA methylation and discoidin domain receptor 1 (DDR1) gene expression in men with nonobstructive azoospermia (NOA). DESIGN: Comparing fibroblasts cultured from testicular biopsies using a high resolution Infinium 450K methylation array. SETTING: Basic research laboratory. PATIENT(S): Men with NOA (n = 16) and with normal spermatogenesis (n = 5)....
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