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Article

Disease modeling and phenotypic drug screening for diabetic cardiomyopathy using human induced pluripotent stem cells.

Cell reports - 6 Nov 2014

Drawnel Faye M, Boccardo Stefano, Prummer Michael, Delobel Frédéric, Graff Alexandra, Weber Michael, Gérard Régine, Badi Laura, Kam-Thong Tony, Bu Lei, Jiang Xin, Hoflack Jean-Christophe, Kiialainen Anna, Jeworutzki Elena, Aoyama Natsuyo, Carlson Coby, Burcin Mark, Gromo Gianni, Boehringer Markus, Stahlberg Henning, Hall Benjamin J, Magnone Maria Chiara, Kolaja Kyle, Chien Kenneth R, Bailly Jacques, Iacone Roberto

Abstract excerpt

Diabetic cardiomyopathy is a complication of type 2 diabetes, with known contributions of lifestyle and genetics. We develop environmentally and genetically driven in vitro models of the condition using human-induced-pluripotent-stem-cell-derived cardiomyocytes. First, we mimic diabetic clinical...

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Identifiers

PMID: 25437537
DOI: 10.1016/j.celrep.2014.09.055

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25437537-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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