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Article

In vitro and in vivo replication of a chemically synthesized consensus genome of hepatitis B virus genotype B.

Journal of virological methods - 1 Mar 2015

Zhang Zhenhua, Xia Jianbo, Sun Binghu, Dai Yu, Li Xu, Schlaak Joerg F, Lu Mengji

Abstract excerpt

Hepatitis B virus (HBV) genotypes vary in their geographical distribution and virological features. Previous investigations have shown that HBV genotype B is a predominant HBV genotype in China. Studies on HBV concerning different isolates frequently meet the question about the HBV reference strain and its representativeness. Although HBV consensus sequences can be generated easily by sequence alignment, they may...

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Identifiers

PMID: 25433217
DOI: 10.1016/j.jviromet.2014.11.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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