Article
Neurocognitive performance in family-based and case-control studies of schizophrenia.
Schizophrenia research - 1 Apr 2015
Gur Ruben C, Braff David L, Calkins Monica E, Dobie Dorcas J, Freedman Robert, Green Michael F, Greenwood Tiffany A, Lazzeroni Laura C, Light Gregory A, Nuechterlein Keith H, Olincy Ann, Radant Allen D, Seidman Larry J, Siever Larry J, Silverman Jeremy M, Sprock Joyce, Stone William S, Sugar Catherine A, Swerdlow Neal R, Tsuang Debby W, Tsuang Ming T, Turetsky Bruce I, Gur Raquel E
Abstract excerpt
BACKGROUND: Neurocognitive deficits in schizophrenia (SZ) are established and the Consortium on the Genetics of Schizophrenia (COGS) investigated such measures as endophenotypes in family-based (COGS-1) and case-control (COGS-2) studies. By requiring family participation, family-based sampling may result in samples that vary demographically and perform better on neurocognitive measures. METHODS: The Penn...
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