Article
Defining adult asthma endotypes by clinical features and patterns of volatile organic compounds in exhaled air.
Respiratory research - 28 Nov 2014
Meyer Norbert, Dallinga Jan W, Nuss Sarah Janine, Moonen Edwin J C, van Berkel Joep J B N, Akdis Cezmi, van Schooten Frederik Jan, Menz Günter
Abstract excerpt
BACKGROUND: Several classifications of adult asthma patients using cluster analyses based on clinical and demographic information has resulted in clinical phenotypic clusters that do not address molecular mechanisms. Volatile organic compounds (VOC) in exhaled air are released during inflammation in response to oxidative stress as a result of activated leukocytes. VOC profiles in exhaled air could distinguish...
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