Phenotyping and Endotyping Asthma Based on Biomarkers.

doi:10.2174/1568026616666150930120803

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Article

Phenotyping and Endotyping Asthma Based on Biomarkers.

Current topics in medicinal chemistry - 1 Jan 2016

Perlikos Fotis, Hillas Giorgos, Loukides Stelios

Abstract excerpt

Asthma is a chronic inflammatory airways disorder mainly characterized by heterogeneity. A phenotype is defined as a group of patients that present similar clinically observable characteristics, without establishing a direct etiologic relationship with a distinct pathophysiologic mechanism. An endotype, on the other hand, describes a subgroup that shares the same pathophysiologic processes that lead to the...

Topics

Asthma
Biomarkers
Endophenotypes
Humans
Phenotype

Source

Open in PubMed

Identifiers

PMID: 26420366
DOI: 10.2174/1568026616666150930120803

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