Article
Asthma phenotypes and endotypes: an evolving paradigm for classification.
Discovery medicine - 1 Apr 2013
Corren Jonathan
Abstract excerpt
Asthma is a common chronic disease characterized by intermittent chest symptoms, variable airways obstruction, and bronchial hyperresponsiveness. Research performed over the past one to two decades has sought to better understand the heterogeneous clinical nature of asthma. Whereas older attempts at phenotyping asthma emphasized the duality of allergic vs. non-allergic asthma, more recent non-biased analyses have...
Topics
- Airway Obstruction
- Asthma
- Biomarkers
- Bronchial Hyperreactivity
- Cluster Analysis
- Cytokines
- Gene Expression Regulation
- Humans
- Hypersensitivity
- Inflammation
- Phenotype
- Pulmonary Medicine