Article
Analysis of association of MEF2C, SOST and JAG1 genes with bone mineral density in Mexican-Mestizo postmenopausal women.
BMC musculoskeletal disorders - 28 Nov 2014
Velázquez-Cruz Rafael, Jiménez-Ortega Rogelio F, Parra-Torres Alma Y, Castillejos-López Manuel, Patiño Nelly, Quiterio Manuel, Villarreal-Molina Teresa, Salmerón Jorge
Abstract excerpt
BACKGROUND: Osteoporosis, a disease characterized by low bone mineral density (BMD), is an important health problem in Mexico. BMD is a highly heritable trait, with heritability estimates of 50-85%. Several candidate genes have been evaluated to identify those involved in BMD variation and the etiology of osteoporosis. This study investigated the possible association of single-nucleotide polymorphisms (SNPs) in...
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