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The Enterovirus 71 Procapsid Binds Neutralizing Antibodies and Rescues Virus Infection <i>In Vitro</i>

27 Nov 2014

Abstract excerpt

UNLABELLED: Enterovirus 71 (EV71) is responsible for seasonal outbreaks of hand, foot, and mouth disease in the Asia-Pacific region. The virus has the capability to cause severe disease and death, especially in young children. Although several vaccines are currently in clinical trials, no vaccines or therapeutics have been approved for use. Previous structural studies have revealed that two antigenically distinct...

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PMID: 25428877
DOI: 10.1128/jvi.03098-14

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