Article
Insect-specific production of new GameXPeptides in photorhabdus luminescens TTO1, widespread natural products in entomopathogenic bacteria.
Chembiochem : a European journal of chemical biology - 19 Jan 2015
Nollmann Friederike I, Dauth Christina, Mulley Geraldine, Kegler Carsten, Kaiser Marcel, Waterfield Nick R, Bode Helge B
Abstract excerpt
Discovery of new natural products by heterologous expression reaches its limits, especially when specific building blocks are missing in the heterologous host or the production medium. Here, we describe the insect-specific production of the new GameXPeptides E-H (5-8) from Photorhabdus luminescens TTO1, which can be produced heterologously from expression of the GameXPeptide synthetase GxpS only upon...
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