Article
Identification of NoxD/Pro41 as the homologue of the p22phox NADPH oxidase subunit in fungi.
Molecular microbiology - 1 Mar 2015
Lacaze Isabelle, Lalucque Hervé, Siegmund Ulrike, Silar Philippe, Brun Sylvain
Abstract excerpt
NADPH oxidases (Nox) are membrane complexes that produce O2(-). Researches in mammals, plants and fungi highlight the involvement of Nox-generated ROS in cell proliferation, differentiation and defense. In mammals, the core enzyme gp91(phox)/Nox2 is associated with p22(phox) forming the flavocytochrome b558 ready for activation by a cytosolic complex. Intriguingly, no homologue of the p22(phox) gene has been...
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