NADPH oxidase homologs are required for normal cell differentiation and morphogenesis in Dictyostelium discoideum.

doi:10.1016/j.bbamcr.2005.02.004

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Article

NADPH oxidase homologs are required for normal cell differentiation and morphogenesis in Dictyostelium discoideum.

Biochimica et biophysica acta - 30 Jun 2005

Lardy Bernard, Bof Mireille, Aubry Laurence, Paclet Marie Hélène, Morel Françoise, Satre Michel, Klein Gérard

Abstract excerpt

Membrane-associated NADPH oxidase complexes catalyse the production of the superoxide anion radical from oxygen and NADPH. In mammalian systems, NADPH oxidases form a family of at least seven isoforms that participate in host defence and signalling pathways. We report here the cloning and the characterisation of slime mould Dictyostelium discoideum homologs of the mammalian heme-containing subunit of...

Topics

Amino Acid Sequence
Animals
Catalysis
Cell Differentiation
Cell Membrane
Cells, Cultured
Cloning, Molecular
Dictyostelium
EF Hand Motifs
Gene Expression Regulation, Developmental
Genes, Protozoan
Isoenzymes
Models, Molecular

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Morphogenesis

Mutation

NADPH Oxidases

Phylogeny

Source

Open in PubMed

Identifiers

PMID: 15950752
DOI: 10.1016/j.bbamcr.2005.02.004

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